Vitamin D Nuclear Receptor and Periodontal Disease
Vitamin
D has received increasing attention in recent years beyond its customary role
in bone metabolism. There has been an explosion of scientific evidence which
suggests the profound role that vitamin D plays in immune homeostasis.
Vitamin
D nuclear Receptor (VDR) has been identified as a ligand-dependent
transcription factor which, in concert with its endogenous ligand, 1,25
hydroxivitamin D (1,25(OH)2D3), is involved in the expression of countless genes.
In view of recent research which revealed that most immune cells express the
vitamin D nuclear receptor (VDR), the authors reviewed the current knowledge
regarding the immunomodulatory effects of vitamin D through its VDR on
peridondontal disease. Read More>>>>>>>>>>
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