Osteoporosis and Periodontal Disease: Association and Mechanisms
Periodontal disease and osteoporosis are multifactorial in their etiology and involve a large strata of the population in India and all over the world. Osteoporosis is a systemic skeletal disease characterized by low bone mass and micro-architectural deterioration of the bone scaffold that results in increased bone fragility and susceptibility to fractures. In osteoporosis, the bone mineral density (BMD) is reduced, bone micro-architecture is disrupted and the amount and variety of non-collagenous proteins in bone is altered while, periodontitis is an inflammation of the supporting tissues of the teeth, usually leading to loss of bone and periodontal ligament and is a major cause of tooth loss and edentulousness in adults. Systemic loss of bone density in osteoporosis including that of the jaw may provide a host system that is increasingly susceptible to infectious destruction of periodontal tissues. Loss of alveolar bone is a prominent feature of periodontal disease while sever...