Journal of Oral Health and Hygiene

In recent months, gum disease has been linked to increasing number of major health problems. Researchers from the University of Louisville School of Dentistry examined the relationship between Porphyromonas gingivalis, a bacterial species that causes gum disease, and esophageal cancer. 

 
gum disease
Gum disease
The team examined the presence of the bacteria’s cell DNA in esophageal tissue, and measured the level of an enzyme unique to P. gingivalis called lysine-gingipain. The cell DNA and lysine-gingipain enzymes were found to be significantly more prevalent in the cancerous tissue of ESCC patients. The researchers also discovered that the bacteria correlated with other factors, including metastasis and overall survival rate. Esophageal cancer is difficult to diagnose, as by the time patients show symptoms —such as difficulty swallowing—most are in very advanced stages of the disease. Read More>>>>>>>>>>

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